Menu Close Menu

Fewer cancers.
Better survival.
Equity for all.

Systemic Anti-Cancer Therapy Regimen Library

LUNG NSCLC Metastatic - vinORELBine [oral] 60 [day 1 and 8] Q3W

Treatment Overview

Cycle 1 (and all further cycles) - 21 days

Cycle length:
21

Cycle details

Cycle 1 (and all further cycles) - 21 days

Medication Dose Route Days Max Duration
ondansetron 8 mg Twice daily oral administration 1, 8
vinORELBine * 60 mg/m² oral administration 1, 8
domperidone 10 mg Three times daily oral administration 1
docusate sodium + sennoside B 2 Tablet(s) oral administration 1

Full details

Cycle 1 (and all further cycles) - 21 days

Day: 1

Medication Dose Route Max duration Details
ondansetron 8 mg Twice daily oral administration
Instructions:

ONE hour before chemotherapy and 8 to 12 hours after chemotherapy. 

vinORELBine * 60 mg/m² oral administration
Instructions:
  • Take with food. Swallow whole with a glass of water, do not crush, chew.
  • KEEP IN FRIDGE - DO NOT FREEZE.
  • Round dose to closest multiple of 20 mg, 30 mg and/or 80 mg capsules.
domperidone 10 mg Three times daily oral administration
Instructions:

When required for nausea and/or vomiting.

  • The choice of rescue antiemetic may be substituted to reflect institutional policy or individual patient characteristics.
docusate sodium + sennoside B 2 Tablet(s) oral administration
Instructions:

At night when required for constipation.

  • Each tablet contains docusate sodium 50 mg + sennoside B 8 mg.

Day: 8

Medication Dose Route Max duration Details
ondansetron 8 mg Twice daily oral administration
Instructions:

ONE hour before chemotherapy and 8 to 12 hours after chemotherapy. 

vinORELBine * 60 mg/m² oral administration
Instructions:
  • Take with food. Swallow whole with a glass of water, do not crush, chew.
  • KEEP IN FRIDGE - DO NOT FREEZE.
  • Round dose to closest multiple of 20 mg, 30 mg and/or 80 mg capsules.

Supportive Care Factors

Factor Value
Constipation risk: laxatives are usually prescribed
Emetogenicity: Medium to high


Regimen details sometimes vary slightly from the published literature after recommendation by expert committee consensus.

* The medicines, doses, combinations, and schedule in this treatment regimen have been carefully reviewed against international best practice guidelines by specialists in medical oncology around New Zealand and this advice has been accepted for publication by Te Aho o Te Kahu (the Cancer Control Agency). Sometimes medicines that are used in routine clinical practice have not been through a formal review process by the NZ Medicines Regulator Medsafe and are therefore considered unapproved or off-label. These medicines are legally able to be prescribed through sections 25 and 29 of the Medicines Act and by obtaining informed consent from patients. All treatment regimens listed on this website have been through robust peer review and are considered an accepted standard of care, whether prescribed through sections 25 or 29 or carrying formal Medsafe Approval.

s29: This symbol indicates that some formulations of the associated medicine are legally only able to be prescribed under section 29 of the Medicines Act. You can see which formulations are section 29 by hovering over the s29 symbol. You can access full medication details from the New Zealand Formulary by clicking on the medication name. Each clinician retains full responsibility for ensuring they have complied with all relevant obligations and requirements of section 29 including obtaining informed patient consent prior to prescribing the applicable medicine.